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Xiao ZX, Chen J, Levine AJ, Modjtahedi N, Xing J, Sellers WR, Livingston DM (1995) Interactionbetween the retinoblastoma protein and the oncoprotein MDM2. After years (late 70s to early80s) of performing immune cell-based experiments on genetically cogenic strains of mice itwas apparent that not only was there an immune response to a growing tumor, but the cellsthat responded (T cells) were the same cell-type that responded to viral infections. A genetic basisand massive release of TNF have been relatedto this reaction

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